To be able to use SharePoint 2010 end users only need a web browser. However, the choice of browser will affect the experience of using SharePoint. Lots of functions are available in all browsers, however there are exceptions where the feature uses Active X technology. This technology has only ever been available in Internet Explorer and means that some of SharePoint's functionality is lost when using non-IE browsers.
Browser support for SharePoint Server 2010 can be divided into three different levels, as follows:
Source: Microsoft Techdoc April 7 2011